Client-side Network Isolation with OpenVPN Client for Windows

[jbenson]

Can someone please tell me whether its possible to enforce a client-side "non-split tunneling" configuration with an OpenVPN client for Windows, and/or direct me to some configuration examples. I have multiple systems connected to the same switch on the same IP network and want to isolate some systems from each other so that when the VPN tunnel to the head-end is active with those systems, there can be no system-to-system communication (East-West) with other systems on the same IP network connected to the same switch that don't have the OpenVPN client installed. Is this even possible with OpenVPN. I've done it before with the Checkpoint, Cisco and Sonicwall VPN clients.

Thanks