Yup – more hassle than any possible benefit that is for sure. Your printer support jumbo? All your switches, do the devices even agree upon the same jumbo size. From what I can tell the makers of the nics and drivers come up with their versions of what the actual size is.. So nic X might not be same as nic Y in computer Z.
Do you really see benefit in the majority of the traffic, dns queries, your gets for your websites. If you look at the types of traffic that flows around your network - where do they make sense.. Unless all you were doing is moving LARGE amounts of data all day long I juts don't see the point of them. Shoot many office networks and homes are like 50% or more wireless these days anyway.
My cheap nics can do 800+ Mbps over the wire at 1500 mtu.. Bottleneck is the drives in moving the data normally, so what performance boost would using jumbo get me?