@greatbush well you can ping other interfaces on pfsense, just not the 172.16.64 one.
At a loss.. You have no floating rules.. And looks like your rule triggered and state are created there in that top rule you posted trying to talk to it.
You have no floating rules - and no current vpn tunnels..
Yeah at a loss to what would cause that.
Can you talk to any of the other 172.16.x interfaces you have via the route table you sent..